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Results for "

gut microbiota

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Bacterial (3) Endogenous Metabolite (7) Fungal (3) Parasite (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Infection (6) Inflammation/Immunology (3) Metabolic Disease (6)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N10521

6'-Sialyllactose	Toll-like Receptor (TLR)	Inflammation/Immunology
6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis .

HY-B1134

Imazalil 1 Publications Verification Enilconazole	Fungal	Infection
Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .

HY-114852

Pheleuin

Endogenous Metabolite Others

Pheleuin (Compound PZN10), a pyrazinone, is found in gut microbiota-derived metabolites .

Pheleuin	Endogenous Metabolite	Others
Pheleuin (Compound PZN10), a pyrazinone, is found in gut microbiota-derived metabolites .

HY-161178

LK-60	Bacterial	Infection
LK-60 is a potent DprE1 inhibitor. LK-60 effectively inhibits the proliferation of Mycobacterium tuberculosis. LK-60 has good safety profiles to gut microbiota and human cells .

HY-148044

UNC10201652	Bacterial	Infection
UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC₅₀ value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes .

HY-B1134A

Imazalil sulfate Enilconazolel sulfate	Fungal	Infection
Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .

HY-125120

Kansuiphorin C

Others Others

Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions .

Kansuiphorin C	Others	Others
Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions .

HY-113270A

Actinine chloride γ-Butyrobetaine chloride; Deoxycarnitine chloride	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Actinine (γ-Butyrobetaine) chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

HY-N4075

O-Desmethylangolensin	Endogenous Metabolite	Metabolic Disease Cancer
O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity .

HY-N0299

Stachyose hydrate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Stachyose hydrate act as a prebiotic to enhance the growth and activity of beneficial bacteria. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota .

HY-113270AS

Actinine-d9 chloride γ-Butyrobetaine-d₉ hydrochloride; Deoxycarnitine-d₉ hydrochloride	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Actinine-d₉ chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

HY-128442

Phenyl sulfate Phenyl hydrogen sulfate	Endogenous Metabolite	Metabolic Disease
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .

HY-N7387

3-Oxocholic acid	Endogenous Metabolite	Metabolic Disease
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-18324

CRS3123 REP-3123	Antibiotic	Inflammation/Immunology
CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections .

HY-W585922

3β-Cholic acid

Others Others

3β-Cholic acid is a derivative of cholic acid (HY-N0324), and can be found in human feces .

3β-Cholic acid	Others	Others
3β-Cholic acid is a derivative of cholic acid (HY-N0324), and can be found in human feces .

HY-115440

CRS3123 dihydrochloride REP-3123 dihydrochloride	Bacterial Antibiotic	Infection
CRS3123 (REP-3123) dihydrochloride, a fully synthetic antibacterial agent, potently inhibits methionyl-tRNA synthetase (MetRS) of Clostridioides difficile, inhibiting Clostridioides difficile toxin production and spore formation. CRS3123 dihydrochloride is an oral agent for the research of Clostridioides difficile infection (CDI) .

HY-13582

Carbendazim 4 Publications Verification	Fungal Parasite	Infection Cancer
Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina . Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .

Gut Microbial Metabolite Library	500 compounds
Accumulating evidence has revealed that intestinal microbiota play an important role in human health and disease, including cardiovascular diseases, inflammatory bowel disease, diabetes, obesity, cancer, and depression, etc. Changes in the composition of gut microbiota associated with disease, referred to as dysbiosis, have been linked to pathologies. Indeed, the gut microbiome functions like an endocrine organ, generating bioactive metabolites which play important roles in human metabolism, health, and disease. Gut microbiome has become a novel therapeutic target for many diseases. Analysis and identification of gut microbial metabolite will contribute to the development of therapeutic methods. In order to meet the need of gut microbiome research, MCE carefully selected a unique collection of 500 gut microbial metabolites. MCE gut microbial metabolite library is a powerful tool for gut microbiome research and gut microbiome -related drug discovery.

Beef extract	Biochemical Assay Reagents
Beef extract is a common ingredient in the preparation of biological culture media .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10521

6'-Sialyllactose	Structural Classification Polysaccharides Endogenous metabolite Saccharides	Toll-like Receptor (TLR)
6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis .

HY-B1134

Imazalil 1 Publications Verification Enilconazole	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Biological Pesticide Research Agricultural Research	Fungal
Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .

HY-125120

Kansuiphorin C	Classification of Application Fields Terpenoids Source classification Other Diseases Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants Disease Research Fields	Others
Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions .

HY-113270A

Actinine chloride γ-Butyrobetaine chloride; Deoxycarnitine chloride	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Actinine (γ-Butyrobetaine) chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

HY-N4075

O-Desmethylangolensin	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity .

HY-N0299

Stachyose hydrate	Structural Classification Polysaccharides Classification of Application Fields Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite
Stachyose hydrate act as a prebiotic to enhance the growth and activity of beneficial bacteria. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota .

HY-128442

Phenyl sulfate Phenyl hydrogen sulfate	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .

HY-N7387

3-Oxocholic acid	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

Cat. No.	Product Name	Chemical Structure

HY-113270AS

Actinine-d9 chloride
Actinine-d₉ chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

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gut microbiota

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products